The class is enjoying a normal summer day at the beach until Ms. Frizzle discovers a letter from "Uncle Shelby," who wants the class to look after his beachfront property. The kids soon discover that this "luxurious" accommodation is only a tiny spot on the shoreline. Why would anyone want to live in a spot where they're battered by waves at high tide and baked by the sun at low tide? To find out, Ms. Frizzle turns the kids into... mussels!?

In the TV show "GOING BATTY," the class is studying nocturnal animals and Ms. Frizzle takes the parents on a nighttime field trip to learn more about bats. As the night progresses, Ralphie becomes convinced that The Friz is a vampire! The class follows Ms. Frizzle and their parents to a scary old castle where, by becoming bats themselves, the kids find out the wonderful truth about these creatures of the night, and Ms. Frizzle!

It's the last day of school before the winter holidays and Wanda plans to see the Nutcracker ballet. But during a trip to a recycling plant that belongs to Murph (Dolly Parton), the toy soldier she needs to get into the theater accidentally gets recycled! Devastated, Wanda wishes for a world without recycling. Ms. Frizzle activates the bus's un-recycler, taking the class and Murph on a song-filled field trip. The importance of recycling hits home when the bus's magic unrecycles everything in Walkerville - including the bus itself, as it too was made from recycled objects! Will the kids find a way to reconstruct the bus in time for Wanda to get back to see the Nutcracker?

When Wanda's pet frog, Bella, jumps out of an open window, Ms. Frizzle shrinks the bus into a mechanical frog and takes her now tiny class on a hop-along adventure in search of Bella and her true home.

When Tim delivers the last of the season's honey to his grandfather's customers, the jars get broken. Tim's solution is simple: get more honey from some bees. But Ms. Frizzle sweetens the idea by turning her class into bees and showing them a beehive up close and personal. When a bear steals the bees' hard-earned supply of honey, the bee-kids discover one last field of nectar-filled flowers. How will the bee-kids communicate this information to the bees in time for them to harvest enough honey before the flowers are killed by the impending frost?

In the TV show "IN A PICKLE," Keesha returns from vacation to find that her prize cucumber has been stolen and was replaced with a smelly old pickle. When the evidence seems to point to Ms. Frizzle as the culprit, the class puts her on trial, with Keesha as prosecutor and Arnold as defense attorney. The Friz says a tiny group of troublemakers called the Mike Robe (microbe) Gang is responsible and takes the class for a visit into the teeny tiny world of microbes. There, they discover that even tiny living things can have a big effect.

"Where did the hot go?" wonders Arnold when he finds that his hot cocoa has cooled. In response, Ms. Frizzle whisks the class to the Arctic! What's the freezing Arctic got to do with heat? While the kids try to find out, the bus's engine freezes and the bus floats away on an ice floe with Ralphie and Phoebe inside! As the bus moves away, so does the heat from everyone's body. How can Ms. Frizzle's kids insulate their body to keep the heat in? Can they rescue Ralphie and Phoebe before they all become the Ice Cube Kids?

Ms. Frizzle's class is visiting the zoo, which is, according to Tim, the only place in the city where wild animals can survive. To test this idea - ZAP! - Ms. Frizzle turns the class into possums, foxes, and falcons! The Bus, with Liz inside, becomes a bear and wanders off, looking for food. Will the kid-animals be able to find the Bus-bear before the zookeeper finds it? And is Tim right? Can animals (like themselves) survive in the city?

Ralphie is crushed when a fever and sore throat keep him home from school the day he's scheduled to host a FNN (Frizzle News Network) television broadcast on health. Not one to let his body get the best of him, Ralphie hosts the show from his bed while his classmates journey through his bloodstream to reveal the news-breaking story of just what's making him sick.

It all starts when Ms. Frizzle's class is rehearsing Concerto for Invented Instrument. Carlos' invented instrument looks great, but sounds ploopy. Ms. Frizzle takes the kids to the Sound Museum - which is a spooky old house on a lonely hill, full of mysterious sounds. The children explore the Soundscape Room, hearing sounds from the jungle, mountains, the sea, and city environments. In another room, the kids feel vibrations when they play giant musical instruments. They put on special glasses and see sound waves in the Sound-O-Vision room. Can Carlos learn how to get the right sound from his musical instrument in time for the concert?

It's a hot and muggy day, and the heat's gone to Ralphie's head. The Friz asks "What makes the weather?" transforms the bus into a Weathermobile, and in a wild ride through the skies gives Ralphie the opportunity to become the meteorological superhero of his dreams.

Flora Whiff (Bebe Neuwirth), the famous expert on smell whose "nose knows" comes to school to judge the First Annual Smell Search. Ms. Frizzle's class creates a unique smell which is bound to take first prize, but Arnold's cousin, Janet, determined to win by herself, changes their smell to an odor only a skunk could love. The kids discover the secret to what makes things smell... now they have to make sure their creation doesn't make a big stink!

There's something dazzling in Ms. Frizzle's closet: a magical, light-powered pinball machine! To win at this game, the kids have to light up all six colors of the rainbow. Now the race is on, as the class shrinks down and zooms into the pinball machine. Catch an eye-full of fun as they try to crack the secret code of what makes color so....colorful!

When Wanda's favorite singer, Molly Cule (Wynonna Judd), comes to town, she chooses Ms. Frizzle's class to wash her famous car. The kids clean it from top to bottom, but when Molly insists they missed a spot, they shrink down to see the molecules that make up the car. Only then can they discover how to clean it down to the very last bit. But time is running out - they'll need a molecular miracle to get the car clean before Molly's concert begins!

It's "Accidental Science Project" day, and the class has brought in marvelously rotten entries from the backs of their refrigerators. Later, when the Friz shrinks the bus down to "take a closer look" at rotting options in an abandoned lot, the class discovers that there's more to rot than first meets the nose.

In the TV show "OUT OF THIS WORLD," Dorothy Ann, an amateur astronomer, discovers that an asteroid she's been tracking is on a collision path with Walkerville Elementary School! Before you can say, "Get messy"! the kids find themselves in outer space, trying to track the path of the asteroid and send it on another course before it destroys the school.

Dorothy Ann loves her physics book. Ralphie loves baseball. Ms. Frizzle ingeniously combines the two in a page-hopping adventure through Dorothy Ann's book to a "Frictionless Baseball Game." The whole class learns about pushes and pulls in a remarkable day at a thoroughly unique ball game.

When the Magic School Bus's engine stops running, Mr. Junkett, a vehicle maintenance inspector, decides the bus should be junked. The class shrinks, dons fireproof suits and masks, and heads for the engine -- from the inside! There, they discover that the peanut-butter that Junkett accidentally dropped into the engine is blocking the fuel line, stopping air from mixing with gas, and keeping the spark plugs from sparking. While cleaning up the mess, the kids learn how an engine works. Can they get the bus working again before Junkett has it pounded into a pancake?

To celebrate the founding of Walkerville, Ms. Frizzle's class sculpts a stone likeness of its founding father, Captain Walker. But as they add the finishing touches, the statue tumbles down the mountain. Ms. Frizzle turns the bus into a giant boulder and the kids into rock kids. They bump down the mountain in a desperate attempt to save the statue. By the time they reach the celebration at the base of the mountain, they've been pushed, tossed, sanded, polished, and eroded by water as has the statue, now the size of a soccer ball. The kids are sure they've let everyone down until they look back at the mountain for the surprise of their lives!

When the kids see Horace Scope (Dabney Coleman) on the Star Shopping Network, they decide to buy Dorothy Ann a real twinkling star for her birthday. Before buying it, the kids blast off in the Bus to inspect the merchandise. They visit a young star and then a middle-age star and decide that it's the third and last star they want to buy. But when they give Horace their money, KABLOOM, the star explodes! Have they lost DA's star forever?